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Chinese ethnic minorities 1

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The Globalization of Traditional Medicines: Perspectives Related to the European Union Regulatory Environment Perspective

Werner Knoess, Jacqueline Wiesner

Engineering 2019, Volume 5, Issue 1,   Pages 22-31 doi: 10.1016/j.eng.2018.11.012

Abstract: The standards defined by the EU herbal monographs of the Committee on Herbal Medicinal Products (HMPCand traditional medicines.medicines from traditional Chinese medicine (TCM) to gain access to the EU market.These developments indicate that globalization of traditional medicines is an ongoing process.This will contribute to worldwide availability of traditional medicines based on appropriate standards

Keywords： Traditional medicine     Traditional Chinese medicine     Committee on Herbal Medicinal Products     Herbal medicines     Traditional medicines     Regulation     Globalization    

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Bioactive Components of Chinese Herbal Medicines in the Treatment of Glucose and Lipid Metabolism Disorders Review

Ying Zhang, Jiaming Ju, Lei Jiao, Baofeng Yang

Engineering 2023, Volume 29, Issue 10,   Pages 73-82 doi: 10.1016/j.eng.2023.03.004

Abstract: Traditional Chinese medicine, mainly Chinese herbal medicine (CHM), has a history of more than 2000 years

Keywords： Chinese herbal medicines     Hyperlipidemia     Hyperglycemia     Cardiovascular and cerebrovascular diseases    

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Research Progress in the Application of Chinese Herbal Medicines in Aquaculture: A Review

Hongyu Pu, Xiaoyu Lia, Qingbo Du, Hao Cui, Yongping Xua

Engineering 2017, Volume 3, Issue 5,   Pages 731-737 doi: 10.1016/J.ENG.2017.03.017

Abstract: As a result, Chinese herbal medicines are being increasingly used, coining the use of the term &ldquo” Research shows that Chinese herbal medicines have many beneficial effects on fish, includingMany effective ingredients have been discovered in Chinese herbal medicines, which function to promoteThis article reviews the latest research and application progress in Chinese herbal medicines regardingThis article concludes by proposing that future studies on Chinese herbal medicines should focus on how

Keywords： Aquaculture     Chinese herbal medicines     Fish farming     Research progress    

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A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment

Yufeng Zhao, Bo Liu, Liyun He, Wenjing Bai, Xueyun Yu, Xinyu Cao, Lin Luo, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 432-439 doi: 10.1007/s11684-017-0511-1

Abstract:

Traditional Chinese patent medicines are widely used to treat stroke because it has good efficacyHowever, because of the lack of knowledge on traditional Chinese patent medicines, many Western physiciansof clinical prescriptions for such medicine, are confused with the use of traditional Chinese patent medicinesThird, the aid-decision model of traditional Chinese patent medicines for stroke treatment is constructedExperimental results reveal that traditional Chinese patent medicines can be differentiated.

Keywords： traditional Chinese patent medicines     stroke     aid decision     data mining     manifold ranking    

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Lingguizhugan Decoction, a Chinese herbal formula, improves insulin resistance in overweight/obese subjects

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 745-759 doi: 10.1007/s11684-021-0880-3

Abstract: Lingguizhugan Decoction (LGZG) has been investigated in basic studies, with satisfactory effects on insulin resistance in non-alcoholic fatty liver disease (NAFLD). This translational approach aimed to explore the effect and underlying mechanism of LGZG in clinical setting. A randomized, double-blinded, placebo-controlled trial was performed. A total of 243 eligible participants with NAFLD were equally allocated to receive LGZG (two groups: standard dose and low dose) or placebo for 12 weeks on the basis of lifestyle modifications. The primary efficacy variable was homeostasis model assessment of insulin resistance (HOMA-IR). Analyses were performed in two populations in accordance with body mass index (BMI; overweight/obese, BMI ≥ 24 kg/m2; lean, BMI < 24 kg/m 2). For overweight/obese participants, low-dose LGZG significantly decreased their HOMA-IR level compared with placebo (−0.19 (1.47) versus 0.08 (1.99),P = 0.038). For lean subjects, neither dose of LGZG showed a superior effect compared with placebo. Methylated DNA immunoprecipitation sequencing and real-time qPCR found that the DNA N6-methyladenine modification levels of protein phosphatase 1 regulatory subunit 3A (PPP1R3A) and autophagy related 3 (ATG3) significantly increased after LGZG intervention in overweight/obese population. Low-dose LGZG effectively improved insulin resistance in overweight/obese subjects with NAFLD. The underlying mechanism may be related to the regulation of DNA N6-methyladenine modification of PPP1R3A and ATG3. Lean subjects may not be a targeted population for LGZG.

Keywords： insulin resistance     non-alcoholic fatty liver disease     Chinese herbal medicine     randomized controlled    

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Prospect in Creating New Drugs from Chinese Herbal Medicine

Yu Dequan

Strategic Study of CAE 1999, Volume 1, Issue 2,   Pages 87-90

Abstract: search for bioactive constituents or leading compounds from natural sources especially from Chinese herbal

The key point of study on the chemical constituents of individual Chinese herbal medicine hasStudy on the bioactive principle of Chinese herbal medicine involves an integration of chemical study

Keywords： natural product research     creating new drug     chemical constituent of Chinese herbal medicine     modem spectroscopic    

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Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019

Guohua Chen, Wen Su, Jiayao Yang, Dan Luo, Ping Xia, Wen Jia, Xiuyang Li, Chuan Wang, Suping Lang, Qingbin Meng, Ying Zhang, Yuhe Ke, An Fan, Shuo Yang, Yujiao Zheng, Xuepeng Fan, Jie Qiao, Fengmei Lian, Li Wei, Xiaolin Tong

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 752-759 doi: 10.1007/s11684-020-0813-6

Abstract: This study aimed to evaluate the efficacy of Chinese herbal medicine (CHM) in patients with severe/critical

Keywords： COVID-19     CHM     mortality     a retrospective cohort study    

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Innovative development path of ethnomedicines: an overview of ethnomedicines in China

Zhaoyun Zhu,Ting Wang,Dehuan Fu,Yali Gui,Jingkun Wang,Tao Cui

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 166-177 doi: 10.1007/s11684-016-0448-9

Abstract: and treatment, ancestral populations worldwide have gained knowledge and experiences in traditional medicinesFor instance, ethnomedicines of Chinese ethnic minorities constitute an important part of traditional medicines

Keywords： traditional medicines     ethnomedicines     Chinese ethnic minorities     ethnopharmacology     research mode     innovative    

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The Scientific Foundation of Chinese Herbal Medicine against COVID-19 Perspective

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Engineering 2020, Volume 6, Issue 10,   Pages 1099-1107 doi: 10.1016/j.eng.2020.08.009

Abstract: Here, we summarize the potential uses and therapeutic mechanisms of Chinese herbal formulas (CHFs) from

Keywords： Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus     Chinese herbal medicine     Antiviral    

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Symptom network topological features predict the effectiveness of herbal treatment for pediatric cough

Mengxue Huang, Jingjing Wang, Runshun Zhang, Zhuying Ni, Xiaoying Liu, Wenwen Liu, Weilian Kong, Yao Chen, Tiantian Huang, Guihua Li, Dan Wei, Jianzhong Liu, Xuezhong Zhou

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 357-367 doi: 10.1007/s11684-019-0699-3

Abstract: Pediatric cough is a heterogeneous condition in terms of symptoms and the underlying disease mechanisms. Symptom phenotypes hold complicated interactions between each other to form an intricate network structure. This study aims to investigate whether the network structure of pediatric cough symptoms is associated with the prognosis and outcome of patients. A total of 384 cases were derived from the electronic medical records of a highly experienced traditional Chinese medicine (TCM) physician. The data were divided into two groups according to the therapeutic effect, namely, an invalid group (group A with 40 cases of poor efficacy) and a valid group (group B with 344 cases of good efficacy). Several well-established analysis methods, namely, statistical test, correlation analysis, and complex network analysis, were used to analyze the data. This study reports that symptom networks of patients with pediatric cough are related to the effectiveness of treatment: a dense network of symptoms is associated with great difficulty in treatment. Interventions with the most different symptoms in the symptom network may have improved therapeutic effects.

Keywords： pediatric cough     complex network     symptoms     traditional Chinese medicine     electronic medical records    

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Systematic review for geo-authentic Lonicerae Japonicae Flos

Xingyue Yang, Yali Liu, Aijuan Hou, Yang Yang, Xin Tian, Liyun He

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 203-213 doi: 10.1007/s11684-017-0504-0

Abstract: medicine, Lonicerae Japonicae Flos is commonly used as anti-inflammatory, antiviral, and antipyretic herbal

Keywords： Lonicerae Japonicae Flos     geo-authentic     herbal quality     chemical fingerprint     component analysis    

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Integrated Platform for Small-Molecule Screening Reveals Potential Targets of Bioactive Compounds from a Herbal Article

Hui Xiong, Ai-Hua Zhang, Ya-Jing Guo, Xiao-Hang Zhou, Hui Sun, Le Yang, Heng Fang, Guang-Li Yan, Xi-Jun Wang

Engineering 2021, Volume 7, Issue 9,   Pages 1293-1305 doi: 10.1016/j.eng.2020.12.016

Abstract:

A herbal prescription in traditional Chinese medicine (TCM) has great complexity, with multiple componentssuccessfully applied for the effective discovery of the active compounds and therapeutic targets of an herbal

Keywords： Efficacy     Bioactive compound     Small molecule     Targets     Herbal medicine     Metabolomics    

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Enhancing Clinical Efficacy through the Gut Microbiota: A New Field of Traditional Chinese Medicine Review

Yan-Meng Lu, Jiao-Jiao Xie, Cong-Gao Peng, Bao-Hong Wang, Kai-Cen Wang, Lan-Juan Li

Engineering 2019, Volume 5, Issue 1,   Pages 40-49 doi: 10.1016/j.eng.2018.11.013

Abstract:

Traditional Chinese medicines (TCMs) have a long history of playing a vital role in disease prevention

Keywords： Traditional Chinese medicines     Gut microbiome     Fatty liver disease     Ulcerative colitis     Obesity     Diabetes    

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Effects of Medicines and Supplements on Spontaneous Pregnancy and Semen Parameters in Male Infertility Article

Jian Li, Qi Wu, Ernest Hung Yu Ng, Ben Willem J. Mol, Xiao Ke Wu, Chi Chiu Wang

Engineering 2022, Volume 16, Issue 9,   Pages 198-209 doi: 10.1016/j.eng.2021.07.009

Abstract:

In this study, we used a network meta-analysis (NMA) to compare the effectiveness of medicines andStudies involving randomized controlled trials (RCTs) investigating medicines (mainly follicle-stimulating

Keywords： Male infertility     Medicine     Supplement     Spontaneous pregnancy rate     Sperm parameters    

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The role played by traditional Chinese medicine in preventing and treating COVID-19 in China

Qingwei Li, Han Wang, Xiuyang Li, Yujiao Zheng, Yu Wei, Pei Zhang, Qiyou Ding, Jiaran Lin, Shuang Tang, Yikun Zhao, Linhua Zhao, Xiaolin Tong

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 681-688 doi: 10.1007/s11684-020-0801-x

Abstract: Traditional Chinese medicine (TCM), an ancient system of alternative medicine, played an active role in the prevention and control of COVID-19 in China. It improved the clinical symptoms of patients, reduced the mortality rate, improved the recovery rate, and effectively relieved the operating pressure on the national medical system during critical conditions. In light of the current global pandemic, TCM-related measures might open up a new channel in the control of COVID-19 in other countries and regions. Here, we summarize the TCM-related measures that were widely used in China, including TCM guidelines, the Wuchang pattern, mobile cabin hospitals, integrated treatment of TCM and modern medicine for critical patients, and non-medicine therapy for convalescent patients, and describe how TCM effectively treated patients afflicted with the COVID-19. Effective TCM therapies could, therefore, be recommended and practiced based on the existing medical evidence from increased scientific studies.

Keywords： medicine     COVID-19     Wuchang pattern     mobile cabin hospital     convalescent patients     three formulae and three medicines    

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Title Author Date Type Operation

The Globalization of Traditional Medicines: Perspectives Related to the European Union Regulatory Environment

Werner Knoess, Jacqueline Wiesner

Journal Article

Bioactive Components of Chinese Herbal Medicines in the Treatment of Glucose and Lipid Metabolism Disorders

Ying Zhang, Jiaming Ju, Lei Jiao, Baofeng Yang

Journal Article

Research Progress in the Application of Chinese Herbal Medicines in Aquaculture: A Review

Hongyu Pu, Xiaoyu Lia, Qingbo Du, Hao Cui, Yongping Xua

Journal Article

A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment

Yufeng Zhao, Bo Liu, Liyun He, Wenjing Bai, Xueyun Yu, Xinyu Cao, Lin Luo, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Journal Article

Lingguizhugan Decoction, a Chinese herbal formula, improves insulin resistance in overweight/obese subjects

Journal Article

Prospect in Creating New Drugs from Chinese Herbal Medicine

Yu Dequan

Journal Article

Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019

Guohua Chen, Wen Su, Jiayao Yang, Dan Luo, Ping Xia, Wen Jia, Xiuyang Li, Chuan Wang, Suping Lang, Qingbin Meng, Ying Zhang, Yuhe Ke, An Fan, Shuo Yang, Yujiao Zheng, Xuepeng Fan, Jie Qiao, Fengmei Lian, Li Wei, Xiaolin Tong

Journal Article

Innovative development path of ethnomedicines: an overview of ethnomedicines in China

Zhaoyun Zhu,Ting Wang,Dehuan Fu,Yali Gui,Jingkun Wang,Tao Cui

Journal Article

The Scientific Foundation of Chinese Herbal Medicine against COVID-19

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Journal Article

Symptom network topological features predict the effectiveness of herbal treatment for pediatric cough

Mengxue Huang, Jingjing Wang, Runshun Zhang, Zhuying Ni, Xiaoying Liu, Wenwen Liu, Weilian Kong, Yao Chen, Tiantian Huang, Guihua Li, Dan Wei, Jianzhong Liu, Xuezhong Zhou

Journal Article

Systematic review for geo-authentic Lonicerae Japonicae Flos

Xingyue Yang, Yali Liu, Aijuan Hou, Yang Yang, Xin Tian, Liyun He

Journal Article

Integrated Platform for Small-Molecule Screening Reveals Potential Targets of Bioactive Compounds from a Herbal

Hui Xiong, Ai-Hua Zhang, Ya-Jing Guo, Xiao-Hang Zhou, Hui Sun, Le Yang, Heng Fang, Guang-Li Yan, Xi-Jun Wang

Journal Article

Enhancing Clinical Efficacy through the Gut Microbiota: A New Field of Traditional Chinese Medicine

Yan-Meng Lu, Jiao-Jiao Xie, Cong-Gao Peng, Bao-Hong Wang, Kai-Cen Wang, Lan-Juan Li

Journal Article

Effects of Medicines and Supplements on Spontaneous Pregnancy and Semen Parameters in Male Infertility

Jian Li, Qi Wu, Ernest Hung Yu Ng, Ben Willem J. Mol, Xiao Ke Wu, Chi Chiu Wang

Journal Article

The role played by traditional Chinese medicine in preventing and treating COVID-19 in China

Qingwei Li, Han Wang, Xiuyang Li, Yujiao Zheng, Yu Wei, Pei Zhang, Qiyou Ding, Jiaran Lin, Shuang Tang, Yikun Zhao, Linhua Zhao, Xiaolin Tong

Journal Article